Dr. Portia Mahal G. Sabido
Position: Assistant Professor
Education: Ph.D., University of Nevada, USA, 1997
Understanding the mechanism of action of receptor-like antibacterial agents (vancomycin and bacitracin) and improving upon their function.
Utilize combinatorial chemistry to accelerate the discovery of antibacterial agents with increase potency towards resistant organisms .
Synthesize derivatives of the drug vancomycin and develop a novel way to counteract drug resistance.
Synthesize the antibacterial agent bacitracin and its analogs in a biomimetic fashion using solid phase peptide synthesis
Cunningham, O., Dunne, A., Sabido, P., Lightner, D., Mantle, T.J., “Studies on the Specificity of the Tetrapyrrole Substrate for Human Biliverdin-IX Reductase and Biliverdin-IX Reductase ” (2000) J. Biochem. 275, 19009-19017.
Sabido, P.M., Lightner, D.A. “Total Synthesis of Mesobilirubin XII and Mesobilirubin XIII.” National Proceeding, 17th Annual Philippine Chemistry Congress, May 22-24, 2001 Manila Hotel.
Quibuyen, T.A.O., Sabido, P.M.F, Felipe, M.J.L. “Synthesis of Vancomycin Analogues with Potential Antimycobacterial Activity.” Proceedings of the 8th Annual Convention of the Natural Products Society of the Philippines.
Quibuyen, T.A.O., Sabido, P.M.F, Felipe, M.J.L. “Synthesis of N-propylguanine Vancomycin Dimers.” February 2001. International Proceedings. Analytical Science Gateway to New Domains Proceedings of the Asia-Pacific Conference on Analytical Science.
Magpusao, A.N., Sabido, P.M.G., Endoma, M.A.A; Concepcion, G.P. “Synthesis of Benzyl Ester Derivative of Heptyl Prodigiosin.” April 2005. Proceedings 20th Annual Philippine Chemistry Congress
Magpusao, A.N.; PMG Sabido, P.M.G., Endoma, M.A.A; Concepcion, G.P. “Synthesis of HPDG (Heptyl Prodigiosin) Analogs.” April 2006. Proceedings 21st Annual Philippine Chemistry Congress.
Magpusao, A.N.; Sabido, P.M.G., Endoma, M.A.A; Concepcion, G.P. “Synthesis of Ester Derivatives of Heptyl Prodigiosin.” April 2006. Proceedings 21st Annual Philippine Chemistry Congress.
Magpusao, A..N.; Arias, M.A.E.; Concepcion, G.P.; Sabido, P.M.G. “Synthesis of Nor-Heptyl Prodigiosin.” February 2007. Proceedings 27th Annual PAASE International Conference.
Francisco, J.T., Micabalo, I., Magpusao, A.N., Arias-Endoma, M.A., Concepcion, G.P., Argayosa, V.B., Sabido, P.M.G. “Isolation of Nor-Prodigiosin from UV-Mutated Serratia marcescens.” April 2007. Proceedings 22nd Annual Philippine Chemistry National Congress.
Tan MAO; Sabido PMDG. Pyrazinoylation and Benzylation of Anoplin: A plausible approach of preparing novel potente antibacterial drugs. June 7-12, 2009. Proceedings of the 21st American Peptide Society Symposium.
Garcia JKL., Sabido PMG.; Santiago AGG. Solid Phase Synthesis and Secondary Structure Prediction of the Cytotoxic Pentapeptide Longicalycinin A. Submitted to Science Diliman.
Magpusao, A.N., Endoma, M.A.A; Concepcion, G.P., PMG Sabido, P.M.G; Synthesis of Derivatives of Heptyl Prodigiosin with Anticancer Activity. Submitted to Philippine Science Letters